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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays by 6 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays by 8 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org.

Support NPR's reporting by subscribing to Up First+ and unlock sponsor-free listening. Learn more at plus.npr.org/upfirst

Most Recent Episodes

Arab Leaders on Israel-Hamas, Trump Won't Testify, Argentina Inauguration

World policy leaders meeting in Qatar discuss the Gaza war and its impact on regional security. Donald Trump plans to skip testifying for a second time in the New York civil fraud trial against him and his company. And Argentine President Javier Milei is inaugurated after promises of big changes to his country struggling with an economic crisis.

Arab Leaders on Israel-Hamas, Trump Won't Testify, Argentina Inauguration

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Samantha and Ariane Buck of Peoria, Ariz., say they were turned away from a physician's office because of money they owed, forcing them to seek emergency care. In 2022, they estimated they had about $50,000 in medical debt. Ash Ponders for KHN and NPR hide caption

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The Sunday Story: The Unbearable Weight of Medical Debt

Today on The Sunday Story host Ayesha Rascoe explores the growing crisis of medical debt in America. Nationwide, 100 million people have health care debt, according to a KHN-NPR investigation, which has documented a crisis that is driving Americans from their homes, draining their savings, and preventing millions from accessing care they need.

The Sunday Story: The Unbearable Weight of Medical Debt

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Gaza Detainees, Sickle Cell Breakthrough, Student Debt Reform

Images of Palestinian men stripped to their underwear prompt outrage. Genetic editing leads to new treatments for blood ailment. Income-based plan zeroes out payments for millions of borrowers.

Gaza Detainees, Sickle Cell Breakthrough, Student Debt Reform

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Hunter Biden Charged, Israel-Hamas War, Antisemitism And Universities

The Justice Department has charged President Biden's son on nine counts related to his failure to pay federal taxes. Israeli military soldiers and Hamas militants fight in urban combat. And the presidents of Harvard, MIT, and The University of Pennsylvania face backlash over comments made during a House hearing on campus antisemitism.

Hunter Biden Charged, Israel-Hamas War, Antisemitism And Universities

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4th GOP Debate, Alleged Sexual Violence By Hamas, McCarthy To Leave Congress

Republican presidential candidates take to the stage for the fourth primary debate. Israeli officials blast the international community for its response to allegations of sexual violence perpetrated by Hamas. And former House Speaker Kevin McCarthy decides to leave Congress.

4th GOP Debate, Alleged Sexual Violence By Hamas, McCarthy To Leave Congress

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Aid To Ukraine, Sen. Tuberville and Military Promotions, Fourth Republican Debate

Some U.S. lawmakers question whether aid to Ukraine should continue amid a battlefield stalemate. Sen. Tommy Tuberville drops his hold on more than 400 military promotions. And four Republican presidential candidates prepare for a fourth debate in Tuscaloosa, Ala.

Aid To Ukraine, Sen. Tuberville and Military Promotions, Fourth Republican Debate

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Ex-Ambassador Charged As Agent, Houthi Attack, Nelson Mandela's Death Anniversary

The Justice Department accuses former U.S. ambassador Victor Manuel Rocha of working as a "clandestine agent" on behalf of Cuba. The Pentagon says that Houthi rebels from Yemen attacked an American naval destroyer and three commercial ships in the Red Sea. And South Africa marks the 10th anniversary of the death of Nelson Mandela.

Ex-Ambassador Charged As Agent, Houthi Attack, Nelson Mandela's Death Anniversary

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Israel Expands Military Operation, SCOTUS Hears Purdue Pharma Case, Liz Cheney

Israel says it expanded its ground offensive against Hamas to all parts of Gaza. This includes the occupied territory's southern areas, where people fled to in the early days of the war. What does this mean for the civilians in Gaza? The Supreme Court on Monday hears arguments for and against a bankruptcy settlement. It involves Purdue Pharma, maker of the pain medication OxyContin. And former Wyoming Congresswoman Liz Cheney warns about the threat of a second Trump presidency.

Israel Expands Military Operation, SCOTUS Hears Purdue Pharma Case, Liz Cheney

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The Sunday Story: All The Only Ones

In this week's episode, Ayesha shares the latest series out of NPR's Embedded. In "All The Only Ones," Laine Kaplan-Levenson unearths the little-known and often neglected history of trans youth in America. The series follows the lives of young transgender people today and travels back in time to the turn of the 20th century to meet some of the earliest trans youth documented in American history.

The Sunday Story: All The Only Ones

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Fighting Resumes, Harris At Climate Summit, Remembering Sandra Day O'Connor

Fighting between Israel and Hamas has resumed after a seven-day pause. Vice President Kamala Harris speaks at the COP28 climate summit in Dubai. Sandra Day O'Connor is remembered as a champion of women in the law.

Fighting Resumes, Harris At Climate Summit, Remembering Sandra Day O'Connor

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